Posts Tagged ‘ventilatory response

Our study is the first to have assessed in the same OHS individuals different types of sleep respiratory abnormalities, ventilatory responses to CO2, and both subjective and objective measures of sleepiness at baseline and when using NIV. Awake ventilatory responses to CO2 were significantly related to the proportion of hypoventilation during REM sleep. The lower […]

Baseline Anthropometric, Functional, Sleep, and Vigilance Data Fifteen consecutive patients (10 men), with a mean age of 55 ± 9 years were prospectively included (Tables 1-3). They were morbidly obese, had moderate-to-severe daytime hypercapnia without abnormal ventilatory function. They presented with a combination of OSAS (ie, apnea-hypopnea index [AHI], 62 ± 32 events per hour […]

Patients Women or men, between 20 and 65 years of age, presenting with a body mass index (BMI) of > 32 kg/m2 and daytime hypoventilation (ie, Paco2, > 45 mm Hg) in the absence of other known causes of chronic hypoventilation (eg, COPD [FEV1/vital capacity ratio, < 65%] or hypothyroidism) were eligible for the study. […]

Obesity-hypoventilation syndrome (OHS) is defined as a combination of obesity and awake chronic hypoventilation occurring in the absence of other known causes of hypoventilation. The disease remains underrecognized as > 30% of obese hospitalized patients, whatever the cause of hospitalization, actually exhibit an undiagnosed daytime hyper-capnia. Use of health-care resources, and rates of hospitalization and […]