Posts Tagged ‘Hypertension

Metabolic Effects Chlorthalidone represents one of three different types of diuretics. Each type works in a slightly different way, but all diuretics lower the amount of salt and water in the body, thereby helping to reduce blood pressure. Diuretic treatments are not benign, and not every patient can tolerate them. As a class of drugs, […]

The ALLHAT study validated current national hypertension treatment guidelines by demonstrating that using chlorthali-done as the initial treatment was as effective as using a drug from one of the alternative classes of antihypertensive agents known as ACE-inhibitors (lisinopril) and a calcium-channel blocker (amlopidine) in decreasing blood pressure and reducing the incidence of fatal coronary heart […]

Predictably, and with good reason, the outcomes of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (the ALLHAT study), reported in late 2002, drew the interest of media journalists as well as the attention of the medical community and the health care industry. The nation’s leading newspapers and television networks scrambled to provide […]

Our results agree with the previous reports that plasma lipid concentrations are higher among Nigerian hypertensives and diabetics than controls,16-19 and that plasma lipid concentrations are lower in this population than in Caucasians.34’35 Racial variations in plasma lipid concentrations are largely attributable to differ¬ences in the fiber component of diet. Traditional African diet is high […]

The baseline data of patients and controls are shown in Table 1. The controls, normoglycaemic hypertensives, normotensive diabetics and diabetic hypertensives were similar in age, body mass index, and male to female ratio. The duration of diagnosis of hypertension was 6.0 ±3.2 years among the normoglycaemic hypertensives and 5.8 ± 2.2 years among type 2 […]

Patients were made of age and sex-matched indigenous Nigerian normotensive type 2 diabetes mellitus patients; normoglycaemic hypertensives and patients with concurrent type 2 diabetes and hypertension (40 patients per group). They were recruited at the medical outpatients’ clinic of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Northwestern Nigeria. Age and sex-matched volunteers certified clinically and biochemically […]

Clusters of multifaceted metabolic disorders including glucose intolerance, essential hyper tension, central obesity, dyslipidaemia and insulin resistance coined metabolic syndrome have been described among Caucasians. About 10 to 15% and 1 to 2% of Nigerians have hypertension and diabetes mellitus respectively. Both conditions coexist frequently in this population, the prevalence of hypertension among diabetics being […]

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