A total of206 patients were enrolled at 20 Canadian centres in this double-blind, ran dom ized, par al lel de sign study of enalapril versus hctz/ amiloride (Figure 1). Eligible patients entered an initial four-week placebo period during which they took one enalapril placebo tablet and one hctz/ amiloride placebo tablet daily. Figure 1) Trial […]
In the past 10 years, the treatment of mild to moderate essential hypertension has undergone fundamental changes. The focus is now on a more individualized treatment approach, whereas previously a stepped-care approach was taken. Diuretics have been prescribed historically with success; they are still accepted as first-line agents for the treatment of hypertension and are […]
The following targets are currently recommended for reducing blood pressure: • in general, less than 140 mm Hg systolic and less than 90 mm Hg diastolic • for patients with diabetes or chronic kidney disease, less than 130/80 mm Hg Use Combinations of Medications and Lifestyle Modifications to Achieve Blood Pressure Targets Most patients require […]
OLD BUT STILL VERY IMPORTANT MESSAGES OF CHEP Measure Blood Pressure in All Adults at All Appropriate Visits For many Canadians with hypertension, the condition remains undetected; therefore, measure blood pressure in all adults at all appropriate visits.
NEW KEY MESSAGE OF THE 2006 RECOMMENDATIONS: IMPROVE PATIENT ADHERENCE TO ANTIHYPERTENSIVE THERAPIES Adherence with antihypertensive management can be improved by implementing a multipronged approach incorporating the following strategies.
INTRODUCTION Hypertension remains a significant health problem that is projected to become a greater global burden in the next 20 years. The estimated total number of adults with hypertension was 972 million in 2000: 333 million in economically developed countries and 639 million in less economically developed countries. The number of adults with hypertension is […]
Which came first, the chicken or the egg? If diuretics had been a panacea for curing hypertension, it is unlikely that drug companies would have taken on the financial risk of developing alternative classes of antihypertensive drugs. As previously discussed, diuretics alone are often inadequate for controlling hypertension and are contraindicated for, or are not […]