Posts Tagged ‘Helicobacter pylori

One of the more dangerous complications of NSAID-induced peptic ulcers is the risk of bleeding or perforation of the ulcer. A case controlled study evaluating the association of H pylori infection and bleeding peptic ulcers in current users of NSAIDs (including analgesic or antithrombotic doses of acetylsalicylic acid [ASA]) determined that NSAID users who were […]

NSAID use is implicated in approximately 10% to 30% of peptic ulcers, with an increased risk of ulcer in older NSAID users, patients with previous peptic ulcer, and patients who use steroids, high doses of multiple NSAIDs or anticoagulants. The role of H pylori in NSAID-induced ulcers is less clear, but some evidence exists to […]

H pylori is accepted as the primary cause of non-NSAID-induced peptic ulcer disease, with an estimated prevalence of 95% in patients with duodenal ulcers and 84% in patients with gastric ulcers. Indeed, eradication of H pylori in patients with both duodenal and gastric ulcers facilitates ulcer healing, reduces the rate of ulcer recurrence and reduces […]

The discovery in the early 1980s that Helicobacter pylori was associated with peptic ulcer disease prompted investigations of its possible implication in other gastrointestinal disorders, such as nonsteroidal anti-inflammatory drug (NSAID)-induced ulcers, functional dyspepsia, gastroesophageal reflux disease (GERD), gastric mucosa-associated lymphoid tissue (MALT) lymphoma and gastric cancer. Your turn to find out more about the […]