Posts Tagged ‘asthma

Airway Smooth Muscle Contraction Hyperresponsiveness to mast cell-derived mediators (eg, histamine) is a distinctive feature of asthma, but its etiology is unknown. We have studied the effects of mast cell enzymes on airway smooth muscle responsiveness. The original studies are described elsewhere. Addition of mastocytoma supernatant to a muscle bath containing dog bronchial smooth muscle […]

Mast cells have been implicated in asthma and in other inflammatory diseases. Multiple physiologic and pathologic effects have been ascribed to mediators that have been shown to be released from these cells, including histamine, prostaglandin D2, leukotrienes, and platelet-activating factor. During degranulation, cells also release tryptic and chymo-tryptic proteases (“tryptases” and “chymases”) extracellularly. These proteases […]

Asthma inhalers are the main element in treating and control of asthma symptoms. Asthma is a chronic disease that sometimes lasts a lifetime. The disorder results in aggravation of inflammatory process in the airways mixed up with bronchospasms, coughing and increased mucus production. The most important part of the treatment plan aimed at prevention of […]

The world economic crisis that burst out in 2008 didn’t go away without leaving a trace. In the first place who suffered were common customers that felt its results in the financial sphere. Practically all the goods and services rose in price and it deals with pharmaceutical market as well. Various drugs became unaffordable due […]