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European Society of Cardiology
15 Apr2010
SELECTED SESSIONS
Aspirin
Serebruany VL: The risk of bleeding complications after different doses of aspirin (ASA): A post-hoc analysis of 192,036patients enrolled in 31 randomized controlled trials (Abstract P3506) A meta-analysis of 31 randomized trials enrolling 192,000 patients was performed to examine the effect of aspirin doses on bleeding. It was found that low daily doses (equivalent to 81 mg in the U.S.) were remarkably safer than higher ones (above 200 mg), particularly in terms of gastrointestinal (GI) bleeding. Victor L. Serebruany, MD, PhD, from the Sinai Center for Thrombosis Research at Johns Hopkins University in Baltimore, concluded that low daily doses of aspirin were associated with the lowest risk. Doses of 81 mg caused fewer major bleeding events, particularly GI bleeding, than did doses of 325 mg.
- In: Health
- Tags: Cardiology, European Society
Speaker: Uri Elkayam, MD, Professor, and Director, Heart Failure Program, Los Angeles County University of Southern California Medical Center, Los Angeles, California
Nesiritide (Natrecor, Scios), a recombinant form of human B-type natriuretic peptide (BNP), may diminish the increased acute mortality risk associated with worsening renal function in patients with chronic decompensated heart failure.
- In: Health
- Tags: Heart Association, Scientific Sessions
American Heart Association: Superior Outcomes in STEMI after Low-Molecular-Weight Heparin
13 Apr2010
Speaker: Marc S. Sabatine, MD, Associate Physician, Cardiovascular Division, Brigham & Women’s Hospital, and Instructor in Medicine, Harvard Medical School, Boston, Massachusetts
The use of a low-molecular-weight heparin (LMWH) plus other standard therapies, including aspirin and clopidogrel (Plavix) may be associated with improved angiographic outcomes, lower rates of major adverse cardiovascular events, and an absence of excessive major bleeding, compared with the use of unfractionated heparin (UFH) in patients with ST-segment elevation myocardial infarction (STEMI).
- In: Health
- Tags: Heart Association, Scientific Sessions
American Heart Association: Omega-3 Fatty Acid Supplementation Improves Lipid Profile in Overweight Children
12 Apr2010
Speaker: Gary A. Mayman, MD, Associate Professor, Cardiology Section, Department of Pediatrics, University of Nevada School of Medicine, and Co-Director, Children’s Heart Center, Las Vegas, Nevada
A group of overweight children who received a dietary supplement of fish oil containing omega-3 fatty acids (Omega RX, Zone Labs), showed a significant improvement in their lipid profiles, in contrast to children who did not receive the supplementation.
- In: Health
- Tags: Heart Association, Scientific Sessions
American Heart Association
11 Apr2010
Extended-Release Niacin for Dyslipidemic Patients with HIV Infection
Speaker: James H. Stein, MD, Associate Professor, Section of Cardiovascular Medicine, Department of Medicine, University of Wisconsin Medical School, Madison, Wisconsin
Extended-release (ER) niacin (Niaspan, Kos), well known for its value in lowering low-density lipoprotein-cholesterol (LDL-C) and total cholesterol and its ability to increase HDL-cholesterol (HDL-C) in patients with hypercholes-terolemia and mixed dyslipidemia, has proved safe, well tolerated, and effective for treating dyslipidemia in patients with human immunodeficiency virus (HIV) infection who are receiving antiretroviral therapy (ART).
- In: Health
- Tags: Heart Association, Scientific Sessions
American Academy of Pain Medicine: Transdermal Hydromorphone Patch for Acute Postoperative Pain
8 Apr2010
Speaker: Edda Gomez-Panzani, MD, Director of Clinical Research and Development, and Head of Medical Affairs, Altea Therapeutics, Tucker, Georgia
An investigational transdermal hydromorphone patch (Altea Therapeutics) seems to be effective for patients with moderate-to-severe acute pain after knee or hip replacement surgery.
The delivery of hydromorphone through the skin was achieved by Altea’s patented PassPort System, an advanced technique that enhances the permeability of the skin by creating aqueous channels (micropores) through the stratum corneum using thermal ablation via an array of metallic filaments. A short pulse of electrical current is generated from a reusable, hand-held applicator.
- In: Main
- Tags: American Academy, Pain Medicine
Adjunctive Intrathecal Ziconotide: An Alternative Approach to Chronic Pain
Speaker: Alexander A. Krakovsky, MD, PhD, DrSc, Pain Management Specialist, Interventional Pain Management, Galileo Medical Center, San Luis Obispo, California
Adjunctive intrathecal therapy with ziconotide (Prialt, Elan) represents the first of a new class of non-opioid analgesics called N-type calcium-channel blockers. This novel approach is used to treat a variety of debilitating chronic pain conditions.
- In: Main
- Tags: American Academy, Pain Medicine