Onychodystrophy refers to various abnormalities in nail morphology due to changes in the attachment of the nail plate, changes in nail surface or color. They are associated with a variety of conditions such as psoriasis, onychomycosis, lichen planus, alopecia areata, endocrine disorders, and drug photosensitivity, etc. Local contact with irritants and trauma are the most common causes, but chronic idiopathic onychodystrophy is often seen without any associated conditions. Treatment modalities include avoidance of predisposing causes and trauma, keeping nails short, and drug therapy such as topical and intralesional corticosteroid. Intralesional corticosteroid injection produces the most reliable results but the response is only temporary and severe pain upon injection prohibits its use. Other modalities do not yield consistent and reliable results.
Hsu and Huang previously reported on two patients with prolonged histories of chronic idiopathic onycholysis that dramatically improved after 12 weeks ingestion of papaya juice, which is rich in carotene. However, we have not been able to find any studies on the effect of carotene on nail formation and disorders. The present study was carried out to evaluate the clinical efficacy of ingestion of carrot juice, which is an easily obtainable and rich source of carotene, in a larger number of patients with chronic idiopathic onychodystrophy. levitra 10 mg