Treatment of Chronic Idiopathic Onychodystrophy: RESULTS

31 Jan
2011

Ten patients with chronic idiopathic onychody- strophy included 4 males and 6 females whose ages ranged at the time of presentation from 5 to 61 years (mean, 36.3). The average duration of nail changes was 3.64 years. None had any family history of similar changes and no systemic abnormalities were detected in any of the cases. The number of involved nails varied from 1-20 (average 9.5 nails).

Fig. 1. (A) A 40-year-old

Fig. 1. (A) A 40-year-old female presented with distal separation of nail plates in all fingers. (B) Two months after drinking two cups of carrot juice daily, onycholysis and trachyonychia improved strikingly in all fingernails. (C) A 61-year-old female complained of nail atrophy, pterygium and trachyonychia on her first toenail. (D) Two months later, the onychodystrophy had improved remarkably.

We summarized their clinical characteristics and responses to ingestion of carrot juice in Table 1. Out of the 10 patients, 3 experienced 75-100% improvement (Fig. 1) and more than 50% improve­ment was seen in 5 patients. Apcalis Oral Jelly

Table 1. Clinical characteristics and responses to ingestion of carrot juice in patients with chronic idiopathic onychodystrophy

Patient

Sex/Age (years)

Duration of CIO

Site (number of involved nails)

Types of CIO


Treatment duration (months)

Treatment response (grade)

1

F/40

1year

FN (5)

Onycholysis, trachyonychia

4

4

2

M/32

13 years

FN (10)

Onycholysis

2

3

3

F/56

3 years

FN (10)

Koilonychia, onychoschizia

2

2


4


M/11


2 years


FN (10)


Onycholysis, trachyonychia


4

1

5

M/46

1 year

FN (10)

Onychoschizia, trachyonychia

1

1

TN (2)

6

F/46

2years

FN (10)

Beau’s line, nail atrophy

2

1

7

F/61

2 years

TN (1)

Trachyonychia

6

4

8

F/5

5 years

FN (6)

Beau’s line

2

3

TN (10)

9

F/59

5 months

FN (10)

Onycholysis, onychorrhexis

1

2

10

M/7

7 years

FN (1)

Koilonychia, trachyonychia

2

4

The response rate of each nail (a total of 85 nails) was analyzed in Fig. 2. More than 75% improvement was seen in 21.2% of the nails and 20% each showed 50 to 75% and 25 to 50% improvements, respectively. 36.4% showed less than 25% improvement.
cialis 5 mg

Fig. 2. Response

Fig. 2. Response rate of each nail with onychodystrophy after intake of carrot juice (a total of 85 nails in 10 patients).

The treatment duration varied from 1 month to 6 months depending on the patients’ compliance. Interestingly, one case showed initial improvement but recurred when the patient reduced the intake of carrot juice from 2 cups to 1 cup a day. Two months after going back to 2 cups per day, remarkable improvement was seen in all fingernails. However, when she again reduced the amount of juice to 1 cup a day, onycholysis recurred. After she restarted to drink 2 cups of carrot juice daily, onychodystrophy was improved again. In other patients, we could not see recurrences because they wanted to maintain the intake of carrot juice.

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