Six-hundred-four patients were admitted with neurological morbidity consisting of 15.6% out a total of 3,868 patients admitted during the five-year period. One-hundred-ninety-eight patients (32.8%) had incomplete records with regards to outcome. A breakdown of the number of patients per year is shown in Table 1.
Males consisted of 321/604 (53.1%), while females were 283/604 (46.9%), giving a ratio of 1.1:1. The age ranged from one month to 16 years, with modal age group of 1-2 years. Children aged five years and under constituted 77.2% of the patients studied. Neonates were not included, because they are admitted into a special care baby unit that caters to critically ill children in this category. Table 2 shows the age group distribution of the patients. avodart medication
Table 1. Distribution off Patients Admitted per Year
| Year | Number off Neurologic Cases | Percent | Total Number of Admissions |
Percent of Total Admissions |
| 1996 |
76 |
12.6 |
490 |
14.7 |
| 1997 |
133 |
22.0 |
879 |
15.1 |
| 1998 |
130 |
21.5 |
800 |
16.3 |
| 1999 |
120 |
19.9 |
672 |
17.9 |
| 2000 |
85 |
14.1 |
628 |
13.5 |
| 2001 |
60 |
9.9 |
399 |
15.0 |
| Total |
604 |
100.0 |
3,868 |
15.6 |
The three major neurological morbidities seen during the period under study were febrile convulsion, 212/604 (35.1%); cerebral malaria, 169/604 (28.0%); and meningitis, 163/604 (27.0%). Together, these three accounted for 92.0% of all neurological morbidities seen. Other morbidities seen are shown in Table 3.
Table 2. Age Group Distribution of Patients
| Age Group | Number | Percent |
| <1 |
145 |
24.0 |
| >l-2 |
155 |
25.7 |
| >2-3 |
92 |
15.2 |
| >3-5 |
74 |
12.3 |
| >5-10 |
82 |
13.6 |
| >10 |
56 |
9.3 |
| Total |
604 |
100.0 |
In children aged five years and under, febrile convulsion was the most common neurological morbidity (42.5%), followed by cerebral malaria (32.2%) and meningitis (19.9%). In children aged 5-10 years and those above 10 years, meningitis was the commonest, 37.8% and 69.6% respectively. clopidogrel 75 mg
Table 3. Distribution of Neurological Morbidities
| Neurologic Morbidity | Number | Percen |
| Febrile convulsion |
212 |
35.1 |
| Cerebral malaria |
169 |
28.0 |
| Meningitis |
163 |
27.0 |
| Epileptic seizures |
30 |
5.0 |
| Head injury |
7 |
1.2 |
| Encephalitis |
6 |
1.0 |
| Alcohol induced coma |
3 |
0.5 |
| Gullian Barre syndrome | CO |
0.5 |
| Psychosis | CO |
0.5 |
| Tetanus | CO |
0.5 |
| Syncope |
2 |
0.3 |
| Hydrocephalus |
1 |
0.2 |
| ICSOL |
1 |
0.2 |
| Migraine |
1 |
0.2 |
| Total |
604 |
100.0 |
Figure 1 shows the seasonal variation in the incidence of the neurological morbidities. The incidence of febrile convulsion and cerebral malaria was highest in the third quartile of the year (July to September), with febrile convulsion being significantly highest in August, while the incidence of meningitis was about equal in the second, third and fourth quar-tiles (April to December). Of the 406 patients with complete records, 64 (15.8%) died, while 342 (84.2%) were either discharged home or transferred to the main pediatric ward. Cerebral malaria and meningitis accounted for all the deaths, 38/64 (59.4%) and 26/64 (40.6%), respectively. Forty-three (67.2%) of the 64 deaths occurred within 24 hours of admission, while 47 (73.5%) within 48 hours and 17 (26.6%) after 48 hours. Children aged five years and under accounted for 48 (75.0%), while those ages 5-10 years accounted for nine (14.1%); those above 10 years were seven (10.9%). generic simvastatin
Figure 1. Seasonal variation in the incidence of neurologic morbidities