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Neuroendocrine neoplasm have been described in virtually every organ where neuroendocrine cells are distributed throughout the body. It commonly exhibits multiple lines of divergent differentiation. Metastatic neuroendocrine carcinoma from distant sites, such as lung, and colon are high degrade tumors with poor prognosis. Cutaneous metastatic neuroendocrine carcinoma must be differentiated from Merkel cell carcinoma by immunohistochemical stains. Cutaneous metastasis from neuroendocrine carcinoma of visceral origin is rarely described. We herin report a case of skin metastasis of neuroendocrine carcinoma which occurred in a patient with rectal neuroendorine carcinoma.
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