Archive for the ‘Pain’ Category

This study showed that peripheral intravenous KCl infusion caused significantly more pain at the infusion site when administered in sterile water than in saline. The exact mechanism of infusion-related pain and phlebitis is not known. Irritation, inflammation, and damage to the venous endothelium can be caused by the inherent chemical property, pH, or osmolality of […]

After 36 of the intended 60 patients had been enrolled, an interim analysis was conducted. At that time, 7 patients had discontinued the infusion prematurely because of pain. The interim analysis revealed significant differences in pain severity at the end of all 3 infusion periods between the groups (first infusion p = 0.002, second infusion […]

Consecutive inpatients with hypokalemia requiring intravenous potassium replacement were enrolled in the study after they gave informed consent. This consent was given while they were in a combined medical and surgical ward. The study protocol was reviewed and approved by the Hamilton Health Sciences/McMaster University Research Ethics Review Board. Patients who had been prescribed one […]

INTRODUCTION Hypokalemia, one of the most prevalent laboratory abnormalities in clinical practice, is defined as a potassium value of less than 3.6 mmol/L. Hypokalemia occurs in over 20% of hospitalized patients. It can be caused by the loss of total body potassium, usually from the gastrointestinal tract as a result of vomiting, diarrhea, or a […]