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Сytomegalovirus infection remains a major problem after clinical heart transplantation. Especially primary infections may result in serious morbidity and even mortality. Primary infections result from transmission of the virus with an allograft or with blood products from CMV seropositive donors into CMV seronegative recipients. The incidence of CMV disease in the CMV seropositive heart donor/seroneg- [...]

Central cyanosis (blueness of skin, lips, mucous membranes), as opposed to peripheral cyanosis, is always a manifestation of hypoxemia. Except for the relatively uncommon causes of methemoglobinemia, sulfhemoglobinemia, and some hemoglobinopathies, central cyanosis is always accompanied by a low arterial Po2. As a result of hypoxemia an excess amount of hemoglobin is not saturated with [...]

Of the ten original articles published after 1923, all but two reference the Lundsgaard and Van Slyke paper by footnote. Two of the ten articles erroneously compare an arterial value of RHB to the capillary value of Lundsgaard and Van Slyke. One review article also makes this erroneous comparison and as a result states that [...]

“EVer since the discovery that incomplete oxygenation of arterial blood is the cause of central cyanosis, the question has been asked: How much reduced (deoxygenated or unsaturated) hemoglobin (RHB) is needed to generate central cyanosis? The amount commonly quoted, 5 g of RHB/dl of blood, comes from the classic 1923 monograph by Lunds- gaard and Van [...]

The optical density method is commonly used to express ELISA data in the field of mycobacterial disease; we used a similar technique (reflectance densitometry) to express immunoblotting data. In this work, we tried to demonstrate the interest in adjusting immunoglobulin concentrations before testing the samples. Moreover, we think that titration of specific antibodies allows better [...]

Total proteins, IgG and IgA concentrations are shown in Table 1. Each pleural fluid or serum sample was further diluted to the same IgG (0.5 g/L) or IgA (1 g/L) concentration before assaying specific antimy­cobacterial reactivities.

Patients Tiiberculous Pleural Effusions (n = 5): Diagnosis was assessed in two cases by histologic examination of pleural biopsy specimens and confirmed by culture (d,e), in two others by culture of pleural fluid (b,c). In the last case, pleural fluid stained with auramin showed acid-fast bacilli and the diagnosis was confirmed by culture (this patient [...]

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