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Epidemiologic studies have shown an inverse relationship between presence of various cancers and dietary carotenoids or blood carotenoid levels. However, several trials using в-carotene supple­ments did not show protective effects against cancer or cardiovascular diseases. On the contrary, the high risk population (smokers and asbestos workers) in these trials showed an increase in cancer and [...]

Onychodystrophy implies various pathologic pro­cesses of the nails including infectious and noninfectious disorders such as onychomycosis, psoriasis, and allergic and irritant dermatitis. Nail changes may also be a clue to other dermatological or systemic diseases. However, chronic idiopathic onychodystrophy is often seen without any associ­ated conditions and onycholysis and onychorrhexis are two of the most [...]

Ten patients with chronic idiopathic onychody- strophy included 4 males and 6 females whose ages ranged at the time of presentation from 5 to 61 years (mean, 36.3). The average duration of nail changes was 3.64 years. None had any family history of similar changes and no systemic abnormalities were detected in any of the [...]

Patients with chronic idiopathic onychodystrophy visiting the outpatient clinic were evaluated. A complete clinical and mycological examination of each patient was done and onychodystrophy asso­ciated with any cause was excluded. Ten patients with chronic idiopathic onychodystrophy were selected for the study and a total of 85 nails were evaluated. We instructed patients to make a [...]

INTRODUCTION Onychodystrophy refers to various abnormalities in nail morphology due to changes in the attach­ment of the nail plate, changes in nail surface or color. They are associated with a variety of con­ditions such as psoriasis, onychomycosis, lichen planus, alopecia areata, endocrine disorders, and drug photosensitivity, etc. Local contact with irritants and trauma are the [...]

AD is multifactorial, polygenetic skin disorder and is commonly viewed as immunologic in patho­genesis. Examination of skin biopsy samples from patients with AD has shown that S. aureus grows in colonies in the upper layers of the epidermis between keratinocyres. This suggests that an exponential increase in S. aureus could results from failure of the [...]

1) TEWL measurement between involved and uninvolved skin For comparisons of TEWL levels between involved and uninvolved sites in AD, measurements were performed 5 times for each site, repeatedly. The mean TEWL level of healthy donor was 7 g/hm2. The mean TEWL levels increased in both un­involved and involved sites than that of healthy donors, [...]

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