To or some years now, resistive inhalational loads have been used to evaluate the endurance capacity of the inspiratory musculature under exertion. The capacity to sustain the muscular exertion required to inhale depends on the force and duration of the inhalational muscle contraction, which is determined by the pressure-time ratio. It is known that healthy [...]
Following embryonic differentiation, the human nail grows continuously throughout life at a rate of about 0.5 to 1.2 mm per week, slowing down with age. Trauma appears to stimulate growth, while immobilization retards the process. Toenails appear to grow at a third to a half the rate of fingernails, and full replacement from base to [...]
Case 1 A 71-year-old man was brought to the VA Medical Center, Johnson City, by his family, who stated that he had a one-week history of fever, chills, and cough productive of yellow sputum. Prior VA records showed that the patient was a long-term smoker, smoking 1 to 2 packs/day for more than 30 years, [...]
The bedside clinician, searching for clues to the presence of disease, is often rewarded by careful examination of the patients hands. The nails offer many clues to the patients physiology and habits. Yellow pigmentation of the nail plate caused by cigarette smoking is especially common (particularly in our Veterans Administration Hospital); clubbing of a “nicotine [...]
DFSP is an uncommon mesenchymal neoplasm originating in the dermis. About 1,000 cases have been reported since DFSP was first described. It usually occurs as an indurated plaque that slowly increases in size and develops multiple firm nodules. Rarely, the initial plaque may be atrophic or depressed, and this atrophic appearance may persist. Lambert et [...]
A 33-year-old female presented with gray depressed atrophic lesion accompanying a skin-colored pea-sized nodule arising from it, and erythematous indurated plaque with intermittent itching and pricking on her upper back. She had first noticed an asymptomatic erythematous plaque 7 years ago. Later, a skin-colored nodule had developed on the left lateral rim of that lesion [...]
INTRODUCTION Dermatofibrosarcoma protuberans (DFSP) is a slow-growing, locally aggressive tumor marked by its high rate of local recurrence. It usually begins as a red-brown indurated plaque, and develops nodules slowly over many years. Rarely, the initial skin lesion may be atrophic or depressed, and may persist despite the advance stage of tumor. Atrophic DFSP is [...]