The available evidence indicates that Sculptra™ is relatively safe. It is contra-indicated only for individuals with a known hypersensitivity to any of the components of the product.

A 24-week, randomized, open-label, single-center, non-control trial in London, UK, enrolled HIV-positive patients with facial lipoatrophy. The patients were randomly assigned to one of two study arms. Patients in the “immediate-treatment” arm received New-Fill® injections bilaterally overlying the buccal fat pads on day one and then two and four weeks later. Patients in the “delayed-treatment” [...]

Sculptra™ is an injectable implant that contains microparticles of poly-L-lactic acid (PLLA). It is a biodegradable, biocompatible, and immunologically inert synthetic polymer derived from the alpha-hydroxy acid family.

INTRODUCTION
Human immunodeficiency virus (HIV) infection affects approximately one million persons in the U.S. alone. Along with recent advances in HIV treatment options, especially over the past decade, dramatic reductions in HIV-associated morbidity and mortality have been observed. As a result of an increase in life expectancy, however, the severity of side effects from these treatment [...]