Archive for the ‘Disease’ Category

The results of a double-blind trial of intrasphincteric in­jection of botulinum toxin compared with placebo showed that 66% of patients remained in remission six months after treatment, and the mean duration of a favourable response was 1.3 years. After a median follow-up of 2.4 years, only one-third of the patients were still in remission despite […]

Current treatment modalities for achalasia are palliative and aim at improving esophageal emptying by reducing lower esophageal sphincter resistance to passage of the bolus. This effect can be achieved endoscopically by means of either pneumatic dilation or botulinum toxin injection, and surgically by extramucosal myotomy. No firm consensus has been reached yet regarding the choice […]

Idiopathic achalasia is a motility disorder characterized by incomplete relaxation of the lower esophageal sphincter and impaired peristalsis of the esophageal body. Defective eso- phageal emptying leads to progressive dilation and tortuosity of the esophagus. Anatomic and physiological studies sug­gest a dysfunction of the myenteric plexus in these patients, and an autoimmune pathogenesis has been […]

This study suggests that using community supports contrib­utes to a better subjective outcome of surgery for IBD. Use of supportive resources was correlated with a higher quality of life in our sample, which is consistent with the reported value of social support for medical outcomes in general. Furthermore, the survey data suggest that in a […]

Of 92 subjects who completed both the resource question­naire and the IBDQ, 43 (47%) were men and 49 (53%) were women. The mean age was 38.0 years (range 17 to 71 years). The mean age at onset of symptoms was 27.6 years (range six to 68 years). Forty-six (50%) had ulcerative colitis, while 43 (47%) […]

Of 219 patients who underwent surgery for Crohn’s disease or ulcerative colitis at Mount Sinai Hospital, Toronto, On­tario between September 5, 1996 and September, 29 1997, 145 could be contacted by telephone and were invited to participate in the study. Fifteen patients declined. One hun­dred and thirty questionnaires were distributed by mail for self-administration. Participants […]

Use of community resources before inflammatory bowel disease surgery is associated with postsurgical quality of life Peer support has the potential to offer benefits to people with chronic illnesses that are not as readily available through traditional medical settings, such as the perception of shared understanding and the benefits associated with al­truism and modelling. In […]