Archive for the ‘Disease’ Category

Predictably, and with good reason, the outcomes of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (the ALLHAT study), reported in late 2002, drew the interest of media journalists as well as the attention of the medical community and the health care industry. The nation’s leading newspapers and television networks scrambled to provide […]

Crohn’s disease is a chronic disorder that causes inflammation of the gastrointestinal (GI) tract, usually the small intestine and/or colon. Symptoms can include persistent diarrhea, abdominal pain, fever, and rectal bleeding. Loss of appetite and subsequent weight loss may also occur. The disease is not always limited to the GI tract; it sometimes also affects […]

Ulcerative Colitis The Mesalamine Study A formulation designed to provide both sustained and late release in the colon may increase compliance and thus promote better outcomes compared with existing 5-aminosalicylic acid (5-ASA) therapies. William J. Sandborn, MD, Professor of Medicine at the Mayo Clinic in Rochester, Minnesota, noted that existing 5-ASA formulations require inconvenient multiple-daily […]

Gastroduodenal and Esophageal Ulceration The ASTERIX study showed that both gastroduodenal ulcers and esophageal ulcers occur less often in at-risk patients who add esomeprazole (AstraZeneca) to low-dose aspirin than in those who add placebo. Low-dose aspirin reduces recurrent events in patients with cardiovascular or cerebrovascular disease, but it is also associated with an 11% prevalence […]

In conjunction with an echocardiogram, BNP may become the gold standard for diagnosing diastolic dysfunction. As a screening test, BNP for HF may be more diagnostically helpful than the far-more-utilized prostate-specific antigen (PSA), Papanicolaou smears, or mammography used to screen for the corresponding prostate, cervical, and breast cancers. It has a high negative predictive value, […]

The pulmonary artery catheter (РАС), in use for over 30 years and placed in about one million patients yearly, is still the gold standard for obtain ing similar hemodynamic values. But there is little information from large, multicenter randomized trials showing value and improved patient outcome. The potential complications are well documented. They include pulmonary […]

Valuable cardiac information can be obtained from the echocardiogram. The size, shape, and function of the ventricles along with regional wall motion can be attained. The presence of thrombus can often be identified depending on its size and location in these patients who have a high risk for the development of thrombotic events. Identification of […]