Archive for the ‘Airflow Obstruction’ Category

In this study, we examined healthy male volunteers who were relatively young and had normal pulmonary function to evaluate the effect of smoking alone. We used the difference in NO concentration (ANO) as a parameter to determine the degree of airflow obstruction because it is a sensitive indicator of NO synthesis in the respiratory tract. […]

The two groups were age matched, and in both, pulmonary function was within the normal range, but FEVi o% and maximum expiratory flow at 25% and 50% vital capacity were significantly lower in smokers than in nonsmokers. In nonsmokers, the concentration of exhaled NO increased after breath-holding in a time-dependent manner (Fig 1). However, the […]

The experiments were approved by the human ethics committee of our university, and informed consent for participation was obtained from each subject. Nineteen healthy volunteers (all male) were allocated to two groups (Table 1): nonsmoking (n=9, mean [SE] 32.3 [3.4] years) and smoking (n=10,35.1 [1.7] years) subjects. Subjects with an asthmatic component, hypertension, or respiratory […]

Objective: The aim of this study was to examine the relationship between endogenous nitric oxide (NO) level and airflow obstruction in smokers using single-breath measurement of exhaled NO with the sequential breath-holding method. Setting: A university hospital. Patients: Nine nonsmoking and ten smoking healthy volunteers. Measurements: NO in exhaled air was measured using a chemiluminescence […]