Angiosarcoma is an extremely malignant soft tissue sarcoma of endothelial origin. Because of its ambiguous presentation that usually mimics common benign dermatologic conditions, it is often diagnosed late. These sarcomas account for about 1% of all sarcomas and less than 0.1 % of all head and neck cancers. Therefore, the rarity of angiosarcoma may impede early diagnosis. Radiation and chronic lymphedema have been implicated in the development of some cutaneous angiosarcomas. Angiosarcoma is usually found in elderly Caucasian men in their 70s. Angiosarcoma has the highest rate of lymph node metastases of all soft-tissue sarcomas of the head and neck, and distant metastasis may occur in up to 50%, with the lung being the most common site. Prognosis is dismal regardless of histologic type and therapy. Age, patient’s sex, location, and clinical appearance have no effect on prognosis. However, tumor size has been found to correlate with favorable outcome, hence, the need for early diagnosis and aggressive management. The overall five-year survival rate is less than 30%.
We present a case of angiosarcoma in a 50-year-old African-American man who presented to our clinic with a nine-month history of a slow-growing lesion on the right occipitoparietal area of the scalp.
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