Gastroduodenal and Esophageal Ulceration The ASTERIX study showed that both gastroduodenal ulcers and esophageal ulcers occur less often in at-risk patients who add esomeprazole (Nexium drug, AstraZeneca) to low-dose aspirin than in those who add placebo. Low-dose aspirin reduces recurrent events in patients with cardiovascular or cerebrovascular disease, but it is also associated with an [...]