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Archive for March, 2010
Protease inhibitors work at the last stage of the viral reproduction cycle. TPV is an inhibitor of the HIV-1 protease, thereby preventing cleavage of the polyprotein. This inhibition leads to the production of an immature, noninfec-tious virus.
- In: HIV
- Tags: HIV Infection, Tipranavir
The Clinical Use of Tipranavir in HIV Infection
23, Mar 2010INTRODUCTION
Highly active antiretroviral therapy (HAART) has augmented the treatment and outcome of human immunodeficiency virus (HIV-1) infection. The inclusion of protease inhibitors (PIs) with a HAART regimen has been responsible for dramatic reductions in morbidity and mortality in cases of advanced infection. It is estimated that nearly 40 million people worldwide are infected with HIV. [...]
- In: HIV
- Tags: HIV Infection, Tipranavir
Medicare Update: Into the Doughnut Hole part 2
19, Mar 2010All prescription plans are required to offer Medication Therapy Management (MTM) services. Although MTM is aimed at optimizing therapy, including the efficient and effective use of medications, this service, unfortunately, is limited to the following Medicare beneficiaries:
those who are taking multiple medications.
those who have multiple chronic diseases.
those who are likely to incur expenditures of more [...]
- In: Main
- Tags: Medicare Update
Medicare Update: Into the Doughnut Hole
18, Mar 2010The so-called “doughnut hole” in Medicare’s Part D prescription drug benefit is a difficult concept for many people to understand. The term raises such questions as these: What are the exact out-of-pocket requirements? When and where does this doughnut hole begin and end?
- In: Main
- Tags: Medicare Update
Medicare Drug Bill Passes
17, Mar 2010She Democrats won’t even be able to send a Medicare Part D price negotiation bill through Congress, and it is unlikely that President George W. Bush will sign the bill (H.R. 4) that the House of Representatives passed on December 12 by a vote of 255-170. Senator Max Baucus (D-Montana), chairman of the Senate Finance [...]
- In: Drugs
- Tags: Medicare Drug
Problem: A 31-year-old man died after being injected with the wrong contrast medium during an outpatient myelogram (spinal radiography). Myelography is safely performed when non-ionic water-soluble radiographic agents are used, as indicated for this route of administration. However, the intrathecal misadministra-tion of ionic contrast media can result in a syndrome of spasms and convulsions, often [...]
- In: Main
- Tags: Intrathecal Injection
Rimonabant (Acomplia): DOSAGE
15, Mar 2010It is expected that the usual dose of canadian rimonabant will be 20 mg once daily before breakfast. No dosage adjustment is recommended for the elderly, but this agent should be used with caution in patients older than 75 years of age.
- In: Diabetes
- Tags: Cancer, Diabetes, Rimonabant