Archive for February, 2010

Osteoarthritis (OA) is a non-inflammatory disease characterized by progressive loss of joint articular cartilage that results in pain and deformity. The disease is also known as degenerative arthritis, degenerative joint disease (DJD), and osteoarthrosis. Epidemiologic data on OA varies depending on the source but the general consensus is that it is the most common joint [...]

Our results agree with the previous reports that plasma lipid concentrations are higher among Nigerian hypertensives and diabetics than controls,16-19 and that plasma lipid concentrations are lower in this population than in Caucasians.34′35 Racial variations in plasma lipid concentrations are largely attributable to differ¬ences in the fiber component of diet. Traditional African diet is high [...]

The baseline data of patients and controls are shown in Table 1. The controls, normoglycaemic hypertensives, normotensive diabetics and diabetic hypertensives were similar in age, body mass index, and male to female ratio. The duration of diagnosis of hypertension was 6.0 ±3.2 years among the normoglycaemic hypertensives and 5.8 ± 2.2 years among type 2 [...]

Patients were made of age and sex-matched indigenous Nigerian normotensive type 2 diabetes mellitus patients; normoglycaemic hypertensives and patients with concurrent type 2 diabetes and hypertension (40 patients per group). They were recruited at the medical outpatients’ clinic of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Northwestern Nigeria. Age and sex-matched volunteers certified clinically and biochemically [...]

Clusters of multifaceted metabolic disorders including glucose intolerance, essential hyper tension, central obesity, dyslipidaemia and insulin resistance coined metabolic syndrome have been described among Caucasians. About 10 to 15% and 1 to 2% of Nigerians have hypertension and diabetes mellitus respectively. Both conditions coexist frequently in this population, the prevalence of hypertension among diabetics being [...]

Ganciclovir, a synthetic acyclic nucleotide analog of guanine, is phosphorylated to a triphosphate within the cell and acts as an inhibitor of viral DNA synthesis. Preliminary data have shown ganciclovir effective in the treatment of symptomatic congenital CMV infection. A phase II study with ganciclovir showed hearing improvement or stabilization in five of 30 infants [...]

CMV infection can be diagnosed by isolation of the virus from the urine or saliva within the first three weeks of life. This can be accomplished by traditional virus culture methods which may take one to two weeks to obtain a result or rapid culture methods (”shell vial assay”) using centrifugation to enhance infectivity and [...]

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